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Manufacturer

Ambica International Corp.

Origin of Medicine

India

Packing Type

Powder for Inj. (IV) in Vial

Salt Composition
       :  Cyclophosphamide

Description

Cyclophosphamide interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by cyclophosphamide, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Uses

Cyclophosphamide is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cyclophosphamide is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents.

Cyclophosphamide is also used for some kinds of kidney disease.

Side Effects

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • nausea, vomiting
  • signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose
  • signs and symptoms of heart failure like fast, irregular heartbeat, sudden weight gain; swelling of the ankles, feet, hands
  • signs and symptoms of infection like fever; chills; cough; sore throat; pain or trouble passing urine
  • signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
  • signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • confusion
  • decreased hearing
  • diarrhea
  • facial flushing
  • hair loss
  • headache
  • loss of appetite
  • missed menstrual periods
  • signs and symptoms of low red blood cells or anemia such as unusually weak or tired; feeling faint or lightheaded; falls
  • skin discoloration

Works

Cyclophosphamide works by damaging the DNA of cancer cells.

Direction of Use

  • Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor’s advice.
  • Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
  • Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

Warning and Precaution

  • Your condition will be monitored carefully while you are receiving this medicine.
  • You may need blood work done while you are taking this medicine.
  • Drink water or other fluids as directed. Urinate often, even at night.
  • Do not become pregnant while taking this medicine or for 1 year after stopping it. Women should inform their health care professional if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 4 months after stopping it. There is potential for serious side effects to an unborn child. Talk to your health care professional for more information.
  • Do not breast-feed an infant while taking this medicine or for 1 week after stopping it.
  • This medicine has caused ovarian failure in some women. This medicine may make it more difficult to get pregnant. Talk to your health care professional if you are concerned about your fertility.
  • This medicine has caused decreased sperm counts in some men. This may make it more difficult to father a child. Talk to your health care professional if you are concerned about your fertility.
  • Call your health care professional for advice if you get a fever, chills, or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This medicine decreases your body’s ability to fight infections. Try to avoid being around people who are sick.

FAQ

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

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