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Manufacturer

Camber Pharmaceuticals Incorporated

Origin of Medicine

India

Packing Type

Sol'n for Inj. (IV) in Vial

Salt Composition
       :  Sugammadex [HOUSE BRAND]

Description

Sugammadex is a modified gamma cyclodextrin designed to selectively reverse the effects of the neuromuscular blockers rocuronium and vecuronium.

Uses

Sugammadex reverses the effects of certain medications used during surgical procedures to relax your muscles. It is typically administered at the end of surgery to help restore muscle function that may have been temporarily blocked by other medications used during the procedure.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives, skin rash or redness; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • flushing (warmth, redness, or tingly feeling);
  • itching;
  • eye pain, itching, or discomfort; or
  • extreme weakness, weak or shallow breathing.

Common side effects of sugammadex may include:

  • slow heartbeats;
  • nausea, vomiting;
  • pain;
  • headache; or
  • a light-headed feeling, like you might pass out.

Works

It works by forming a complex with these drugs, reducing their availability to bind to nicotinic receptors in the neuromuscular junction. Sugammadex creates a concentration gradient which favors movement of rocurionium from the neuromuscular junction into the plasma, which quickly reverses rocuronium-induced neuromuscular blockade.

Direction of Use

  • Sugammadex is injected into a vein through an IV. A healthcare provider will give you this medicine in a single injection.
  • Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving sugammadex.

Warning and Precaution

You should not use sugammadex if you are allergic to it.

To make sure sugammadex is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • a bleeding or blood clotting disorder such as hemophilia;
  • low levels of platelets in blood; or
  • a breathing disorder.

It is not known whether sugammadex will harm an unborn baby. Tell your doctor if you are pregnant.

Sugammadex can make hormonal birth control less effective. For at least 7 days after you receive sugammadex, use a non-hormonal back-up birth control (condom or diaphragm with spermicide) to prevent pregnancy. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during this time.

FAQ

Q1. What happens if I miss a dose?

Since sugammadex is used as a single dose, it does not have a daily dosing schedule.

Q2. What happens if I overdose?

Since sugammadex is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Q4. What other drugs will affect sugammadex?

Tell your doctor about all your current medicines, especially:

  • toremifene;
  • a blood thinner–warfarin (Coumadin, Jantoven);
  • hormonal birth control–birth control pills, injections, implants, skin patches, vaginal rings; or
  • medicine to prevent blood clots–dabigatran (Pradaxa), rivaroxaban (Xarelto), and others.

Other drugs may interact with sugammadex, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

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