PacliGet Box of 1's

Manufacturer

Venus Remedies Limited

Origin of Medicine

India

Packing Type

Sol'n for Inj. (IV) in Vial

Salt Composition
       :  Paclitaxel

Description

Paclitaxel is a chemotherapy medication used to treat various cancers, including ovarian, esophageal, breast, lung, Kaposi's sarcoma, cervical, and pancreatic cancer. It works by blocking cell division and interfering with microtubules, which are important for maintaining cell structure and normal functioning.

Uses

  • AIDS-related Kaposi sarcoma. It is used as second-line therapy.
  • Breast cancer. It is used:
    • as adjuvant therapy with doxorubicin hydrochloride-containing combination chemotherapy, in patients with node-positive cancer
    • in patients with metastatic cancer that did not respond to combination chemotherapy
  • Non-small cell lung cancer. It is used with cisplatin as first-line therapy in patients whose cancer cannot be treated with surgery or radiation therapy.
  • Ovarian cancer that is advanced. It is used with cisplatin as first-line therapy or alone in patients who have already received other treatment.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Paclitaxel may cause serious side effects. Call your doctor at once if you have:

  • severe stomach pain or diarrhea;
  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • flushing (warmth, redness, or tingly feeling);
  • numbness, tingling, or burning pain in your hands or feet;
  • severe redness or irritation, swelling or a hard lump, or other skin changes where the injection was given (may occur 7 to 10 days after an injection);
  • pain or burning when you urinate;
  • cough with mucus, chest pain, feeling short of breath;
  • chest pain, shortness of breath, fast or slow heartbeats;
  • a light-headed feeling, like you might pass out;
  • severe headache, blurred vision, pounding in your neck or ears;
  • a seizure;
  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • low red blood cells (anemia)–pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
  • low white blood cell counts–fever, mouth sores, skin sores, sore throat, cough, trouble breathing.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects of paclitaxel may include:

  • fever, chills, or other signs of infection;
  • anemia;
  • feeling weak, tired, or light-headed;
  • bleeding;
  • trouble breathing or swallowing;
  • hair loss, skin rash, hives;
  • numbness, tingling, or burning;
  • swelling in your face, hands, or feet;
  • sores or white patches in or around your mouth;
  • joint or muscle pain;
  • nausea, vomiting, diarrhea; or
  • tenderness or irritation where the medicine was injected.

Works

Paclitaxel works by stopping cancer cells from separating into two new cells. This blocks the growth of the cancer.

Direction of Use

  • Paclitaxel is given as an infusion into a vein. A healthcare provider will give you this injection.
  • Paclitaxel must be given slowly, and the infusion can take 3 to 24 hours to complete.
  • Paclitaxel is usually given once every 2 to 3 weeks. Follow your doctor’s dosing instructions very carefully.
  • You may be given other medications to prevent an allergic reaction while you are receiving paclitaxel.
  • Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving paclitaxel.
  • Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when paclitaxel is injected.
  • Paclitaxel can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.

Warning and Precaution

You should not be treated with paclitaxel if you are allergic to it, or if you have:

  • low white blood cell (WBC) counts; or
  • an allergy to castor oil (contained in paclitaxel and other medicines such as cyclosporine or teniposide).

Tell your doctor if you have ever had:

  • heart problems; or
  • liver disease.

Paclitaxel may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

You should not breastfeed while you are using paclitaxel.

FAQ

Q1. What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your paclitaxel injection.

Q2. What happens if I overdose?

Since paclitaxel is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Q3. What should I avoid while using paclitaxel?

Paclitaxel contains alcohol and may cause a drunken feeling when the medicine is injected into your vein. Avoid drinking alcohol on the day of your paclitaxel injection.

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Q4. What other drugs will affect paclitaxel?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect paclitaxel. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

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